1956KbAbstractThe endoplasmic reticulum (ER) is responsible

The first part of the triple crown is the Indianapolis 500 on May 26 and the last part is the 500 mile season finale on Oct. 10 at Auto Club Speedway in Fontana, Calif. If a driver wins all three races, he or she will receive a $1 million bonus. 1956KbAbstractThe endoplasmic reticulum (ER) is responsible for the folding and modifications of numerous proteins produced by the cell. To ensure that only correctly folded proteins proceed to the surface, a highly conserved process called the unfolded protein response (UPR) has been developed. In mammals, signalling in the UPR is induced by membrane embedded stress sensors, IRE1, PERK and ATF6.

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